Reference · Repair
TB-500
TB-500 is a research designation applied to thymosin beta-4, an endogenous 43-amino-acid actin-sequestering peptide assigned the international nonproprietary name timbetasin; some suppliers apply the label to the shorter actin-binding fragment instead. The published record is predominantly preclinical, with rodent dermal wound-repair models among the earliest reports (Malinda et al., Journal of Investigative Dermatology 1999) and rodent corneal injury models examined subsequently. Human data are largely confined to ophthalmic formulations of thymosin beta-4, evaluated in the randomized, placebo-controlled ARISE Phase 3 programme in dry eye. Non-ophthalmic human evidence remains sparse.
Research use only. Not for human or veterinary use. This page describes what the compound is and what published literature has examined; it is not guidance on use.
Chemistry
- Class
- Repair
- CAS number
- 77591-33-4
- Molecular formula
- C212H350N56O78S
- Molecular weight
- 4963.4 g/mol (free acid)
- Sequence
- Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH (43 amino acids)
- Physical form
- Sterile freeze-dried powder
Available as
| Material | Vial | Price | Per mg | Purity | |
|---|---|---|---|---|---|
| TB-500 10mgTB5-10 | 10 mg | $155 | $15.50/mg | ✓ 99.26% | Details → |
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Common questions
What is the CAS number for TB-500?
77591-33-4.
What is the molecular formula and weight of TB-500?
TB-500 has molecular formula C212H350N56O78S and a molecular weight 4963.4 g/mol (free acid).
What is the sequence of TB-500?
Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH (43 amino acids).
What strengths of TB-500 are available?
10 mg, supplied as lyophilised powder. Each carries a measured purity result for the lot in stock.
Is TB-500 approved for human use?
No. TB-500 supplied here is a research material for laboratory use only. It is not approved by the FDA or any other regulator for human or veterinary use, and nothing on this page is guidance on use.