Reference · Repair
PT-141 (Bremelanotide)
Bremelanotide, also designated PT-141, is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH, characterised as an agonist at melanocortin receptors including MC3R and MC4R (Molinoff et al., Annals of the New York Academy of Sciences 2003). Preclinical work examined solicitational and other sexual behaviours in female rats following central melanocortin receptor stimulation (Pfaus et al., Proceedings of the National Academy of Sciences 2004). In humans, a placebo-controlled pilot recorded physiological and subjective arousal measures in premenopausal women with sexual arousal disorder (Diamond et al., Journal of Sexual Medicine 2006), and two randomised Phase 3 trials, RECONNECT 301 and 302, enrolled premenopausal women with hypoactive sexual desire disorder (Kingsberg et al., Obstetrics & Gynecology 2019). Bremelanotide acetate is licensed in the United States as a prescription product; the research-grade peptide is not that pharmaceutical product.
Research use only. Not for human or veterinary use. This page describes what the compound is and what published literature has examined; it is not guidance on use.
Chemistry
- Class
- Repair
- CAS number
- 189691-06-3
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.2 g/mol (free peptide)
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (7 amino acids; N-acetyl norleucine, side-chain lactam between Asp and Lys, free C-terminal acid)
- Physical form
- Sterile freeze-dried powder
Available as
| Material | Vial | Price | Per mg | Purity | |
|---|---|---|---|---|---|
| PT-141 10mgPT141-10 | 10 mg | $62 | $6.20/mg | ✓ 99.76% | Details → |
Flat $20 US shipping, or free local pickup across Southwest Florida and Greater Philadelphia. Request a quote →
Common questions
What is the CAS number for PT-141 (Bremelanotide)?
189691-06-3.
What is the molecular formula and weight of PT-141 (Bremelanotide)?
PT-141 (Bremelanotide) has molecular formula C50H68N14O10 and a molecular weight 1025.2 g/mol (free peptide).
What is the sequence of PT-141 (Bremelanotide)?
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (7 amino acids; N-acetyl norleucine, side-chain lactam between Asp and Lys, free C-terminal acid).
What strengths of PT-141 (Bremelanotide) are available?
10 mg, supplied as lyophilised powder. Each carries a measured purity result for the lot in stock.
Is PT-141 (Bremelanotide) approved for human use?
No. PT-141 (Bremelanotide) supplied here is a research material for laboratory use only. It is not approved by the FDA or any other regulator for human or veterinary use, and nothing on this page is guidance on use.