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Reference · Growth factor

Thymosin Alpha-1

Thymosin Alpha-1 is a 28-amino-acid, N-terminally acetylated acidic peptide first isolated from thymic tissue as part of thymosin fraction 5 (Costantini et al., Frontiers in Oncology 2019). Its synthetic form, thymalfasin, is registered as a medicine in some jurisdictions, though not the United States. Published literature characterises it as an immunomodulator and has examined it in chronic hepatitis B and C, oncology, and critical care settings. Clinical programmes in severe sepsis include the multicentre randomised ETASS trial (Wu et al., Critical Care 2013), and a later meta-analysis pooled 11 randomised trials comprising 1,927 participants (Gu et al., Frontiers in Cellular and Infection Microbiology 2025).

Research use only. Not for human or veterinary use. This page describes what the compound is and what published literature has examined; it is not guidance on use.

Chemistry

Class
Growth factor
CAS number
62304-98-7
Molecular formula
C129H215N33O55
Molecular weight
3108.3 g/mol
Sequence
Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH (28 amino acids)
Physical form
Sterile freeze-dried powder

Available as

MaterialVialPrice Per mgPurity
Thymosin Alpha-1 10mgTHYA-1010 mg$155$15.50/mg✓ 99.11%Details →

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Common questions

What is the CAS number for Thymosin Alpha-1?

62304-98-7.

What is the molecular formula and weight of Thymosin Alpha-1?

Thymosin Alpha-1 has molecular formula C129H215N33O55 and a molecular weight 3108.3 g/mol.

What is the sequence of Thymosin Alpha-1?

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH (28 amino acids).

What strengths of Thymosin Alpha-1 are available?

10 mg, supplied as lyophilised powder. Each carries a measured purity result for the lot in stock.

Is Thymosin Alpha-1 approved for human use?

No. Thymosin Alpha-1 supplied here is a research material for laboratory use only. It is not approved by the FDA or any other regulator for human or veterinary use, and nothing on this page is guidance on use.