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Reference · GLP-1 / GIP

Tirzepatide

Tirzepatide (LY3298176) is a synthetic 39-amino-acid peptide developed by Eli Lilly that acts as a dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors; its structure is based on the native GIP sequence and carries a C20 fatty di-acid modification (Coskun et al., Molecular Metabolism 2018). The United States FDA approved tirzepatide for type 2 diabetes in 2022 (Mounjaro) and for chronic weight management in 2023 (Zepbound). Published phase 3 literature includes the SURPASS programme, which examined glycaemic parameters in participants with type 2 diabetes, and the SURMOUNT programme, which examined body-weight regulation (Jastreboff et al., New England Journal of Medicine 2022).

Research use only. Not for human or veterinary use. This page describes what the compound is and what published literature has examined; it is not guidance on use.

Chemistry

Class
GLP-1 / GIP
CAS number
2023788-19-2
Molecular formula
C225H348N48O68
Molecular weight
4813.5 g/mol (parent peptide)
Sequence
39 amino acids; Aib at 2 & 13; Lys20 lipidated (C20 diacid–γGlu–2×AEEA); C-terminal amide
Physical form
Sterile freeze-dried powder

Available as

MaterialVialPrice Per mgPurity
Tirzepatide 10mgTIRZ-1010 mg$95$9.50/mg✓ 99.08%Details →
Tirzepatide 15mgTIRZ-1515 mg$135$9.00/mg✓ 99.28%Details →
Tirzepatide 20mgTIRZ-2020 mg$155$7.75/mg✓ 99.93%Details →
Tirzepatide 30mgTIRZ-3030 mg$170$5.67/mg✓ 99.28%Details →
Tirzepatide 60mgTIRZ-6060 mg$230$3.83/mg✓ 99.94%Details →

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Common questions

What is the CAS number for Tirzepatide?

2023788-19-2.

What is the molecular formula and weight of Tirzepatide?

Tirzepatide has molecular formula C225H348N48O68 and a molecular weight 4813.5 g/mol (parent peptide).

What is the sequence of Tirzepatide?

39 amino acids; Aib at 2 & 13; Lys20 lipidated (C20 diacid–γGlu–2×AEEA); C-terminal amide.

What strengths of Tirzepatide are available?

10 mg, 15 mg, 20 mg, 30 mg, 60 mg, supplied as lyophilised powder. Each carries a measured purity result for the lot in stock.

Is Tirzepatide approved for human use?

No. Tirzepatide supplied here is a research material for laboratory use only. It is not approved by the FDA or any other regulator for human or veterinary use, and nothing on this page is guidance on use.